Understanding the health effects of GenX and PFAS in communities
Official title: Extending and Maintaining the GenX Exposure Study
Funded at North Carolina State University Raleigh · NIH-11034504 · Data updated 2026-11-12
This study is looking at how chemicals called GenX and PFAS might affect the health of people living in the Cape Fear River area, and it's inviting residents aged 6 and up to give blood samples to help understand these effects better, all while making sure to keep everyone informed and involved in both English and Spanish.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project start | December 16, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $373,534 |
| NIH project number | 1U24ES037001-01 |
| Project ID | NIH-11034504 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include residents of the Cape Fear River Basin, particularly those who have been exposed to GenX and PFAS.
✕Less likely to help
Patients who do not reside in the Cape Fear River Basin or who have not been exposed to GenX or PFAS may not benefit from this research.
What this research studies
This research investigates the potential health impacts of GenX and other per- and polyfluoroalkyl substances (PFAS) on residents in the Cape Fear River Basin. It involves a community-based cohort study where participants, aged 6 and older, provide blood samples for analysis of PFAS levels and related health outcomes. The study aims to enhance community engagement and maintain long-term participation by providing information in both English and Spanish, and by collaborating with local organizations focused on environmental protection. The research will also strengthen the infrastructure for data management and specimen collection.
Why it matters
Potential benefit: If successful, this research could provide valuable insights into the health effects of PFAS exposure, potentially leading to improved public health strategies and policies.
How similar studies have gone: Previous studies on PFAS exposure have shown significant health impacts, indicating that this research builds on established findings rather than being entirely novel.
Where this research is happening
-
North Carolina State University Raleigh
Raleigh, United States Active
Researchers
- Principal investigator: Hoppin, Jane — North Carolina State University Raleigh
- Study coordinator: Hoppin, Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.