Understanding the genetics of von Willebrand disease
Official title: BIOINFORMATICS CORE
Funded at Washington University · NIH-11016810 · Data updated 2026-11-12
This study is looking at the genes and biology behind von Willebrand disease to better understand what causes it, and it's designed for people with this bleeding disorder to help improve their care.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | May 15, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $337,604 |
| NIH project number | 1P01HL173579-01A1 |
| Project ID | NIH-11016810 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with von Willebrand disease or those with a family history of bleeding disorders.
✕Less likely to help
Patients without von Willebrand disease or related bleeding disorders may not receive any benefit from this research.
What this research studies
This research focuses on the genetics and biology of von Willebrand factor and von Willebrand disease. It aims to analyze large cohorts using genomics and multi-omics approaches, which involve extensive bioinformatics analyses. A dedicated Bioinformatics Core will centralize data processing, ensuring that clinical and phenotypic data are standardized and securely managed. The project will facilitate the flow of data and provide insights into the genetic factors influencing this bleeding disorder.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of von Willebrand disease, potentially enhancing treatment options for patients.
How similar studies have gone: Previous research utilizing bioinformatics and multi-omics approaches has shown promise in understanding genetic disorders, indicating potential success for this project.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Stitziel, Nathan Oliver — Washington University
- Study coordinator: Stitziel, Nathan Oliver
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.