Understanding the genetics of psychosis in African populations
Psychosis Genetics Research in Africa: Building Capacity by Investing in People
This study is looking to understand the genetic causes of psychosis, like schizophrenia, by including African communities in the research, so we can find new ways to treat these conditions that work for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10690453 on NIH RePORTER |
What this research studies
This research aims to create a comprehensive neuropsychiatric genetics program across Africa, focusing on understanding the genetic factors associated with psychosis, particularly schizophrenia. By including African populations in genetic studies, the project seeks to identify unique genetic markers and therapeutic signals that have been overlooked in previous research. The methodology involves collecting genetic data and analyzing it to uncover the genetic architecture of neuropsychiatric disorders, which could lead to better-targeted treatments. The initiative also emphasizes the importance of equity in research, ensuring that advancements in neuropsychiatry benefit all populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from African populations who are experiencing symptoms of psychosis or have a family history of neuropsychiatric disorders.
Not a fit: Patients outside of African populations or those without neuropsychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for psychosis in African populations.
How similar studies have performed: Previous research has shown success in genetic studies of neuropsychiatric disorders in other populations, but this approach is novel for African populations.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Koenen, Karestan C — Broad Institute, INC.
- Study coordinator: Koenen, Karestan C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.