Understanding the genetics of osteoarthritis and improving recovery after joint replacement
Genetics of Osteoarthritis and Joint Replacement Recovery: Key to Precision Rehabilitation
This study is looking at how your genes might affect your recovery after joint replacement surgery for osteoarthritis, especially for veterans, so we can create better, personalized rehab plans that work for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Birmingham VA Medical Center NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10851739 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to osteoarthritis (OA) and how these factors can influence recovery after joint replacement surgeries, specifically in veterans. By analyzing data from a large cohort of veterans, the study aims to identify genetic markers that may predict rehabilitation outcomes. The goal is to develop personalized rehabilitation strategies that cater to the unique genetic backgrounds of patients, particularly focusing on diverse populations such as African American and Hispanic veterans. This approach seeks to enhance the quality of life for those affected by OA and improve their post-surgical recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans suffering from end-stage osteoarthritis who are scheduled for total hip or knee arthroplasty.
Not a fit: Patients who do not have osteoarthritis or are not veterans may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to tailored rehabilitation programs that significantly improve recovery outcomes for patients undergoing joint replacement surgery.
How similar studies have performed: Previous research has shown promising results in identifying genetic factors related to osteoarthritis, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- Birmingham VA Medical Center — Birmingham, United States (Active)
Researchers
- Principal investigator: Mcdonald Donnelly, Merry-Lynn Noelle — Birmingham VA Medical Center
- Study coordinator: Mcdonald Donnelly, Merry-Lynn Noelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.