Understanding the genetics of non-alcoholic fatty liver disease
Systems Genetics Dissection of Non-alcoholic Steatohepatitis
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11086834
This study is looking at non-alcoholic fatty liver disease (NAFLD) to understand how our genes and environment work together to affect liver health, with the hope of finding better ways to diagnose and treat this condition for people who have it.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11086834 on ClinicalTrials.gov |
What this research studies
This research investigates non-alcoholic fatty liver disease (NAFLD), a common liver condition that can lead to serious health issues. By using a systems genetics approach, the study aims to uncover how genetic and environmental factors interact to influence the disease. Researchers will analyze genetic variations and their effects on liver health through advanced technologies, which may help identify new treatment targets. The findings could lead to better diagnostic tools and therapies for patients suffering from NAFLD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with non-alcoholic fatty liver disease or those at risk of developing it.
Not a fit: Patients with liver disease caused by excessive alcohol consumption or other non-genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for patients with non-alcoholic fatty liver disease.
How similar studies have performed: Previous research using systems genetics has shown promise in understanding complex diseases, suggesting that this approach could yield valuable insights into NAFLD.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUSIS, ALDONS JAKE — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: LUSIS, ALDONS JAKE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Candidate Disease Gene