Understanding the genetics of leiomyosarcoma to improve diagnosis and treatment
Genetics and Genomics of Leiomyosarcoma (LMS): Improved understanding of cancer biology and new approaches to diagnosis and treatment
This study is looking at how certain gene changes might lead to leiomyosarcoma, a type of soft tissue cancer, and aims to find new ways to diagnose and treat it, with the hope of improving survival and quality of life for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10911933 on NIH RePORTER |
What this research studies
This research focuses on leiomyosarcoma (LMS), a type of soft tissue cancer, by investigating the genetic mutations that contribute to its development. The team aims to understand how changes in specific genes, like TP53, affect the biology of LMS and explore new diagnostic and treatment approaches. By collaborating across multiple institutions, the research seeks to enhance the survival and quality of life for patients with this aggressive cancer. Patients may be involved in clinical studies that test innovative therapies based on these genetic insights.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with leiomyosarcoma, particularly women, Black Americans, and older adults.
Not a fit: Patients with other types of cancer or those not diagnosed with leiomyosarcoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and more effective treatments for leiomyosarcoma patients.
How similar studies have performed: Previous research has shown promise in understanding genetic factors in other cancers, suggesting potential for success in this area as well.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Schuetze, Scott Michael — University of Michigan at Ann Arbor
- Study coordinator: Schuetze, Scott Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.