Understanding the genetics of kidney disease in different ethnic groups
Genetics of kidney disease in diverse populations
This study is looking at how our genes might affect the risk of chronic kidney disease, especially in Hispanic and Latino communities, by analyzing genetic information from over 71,000 people to find out what specific genes could play a role in kidney health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10452691 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to chronic kidney disease (CKD) in diverse populations, particularly focusing on under-studied groups such as Hispanics/Latinos. By analyzing genetic data from over 71,000 participants across various ancestral backgrounds, the study aims to identify specific genetic variants that increase the risk of CKD. The research employs advanced statistical methods to conduct trans-ethnic meta-analyses, which will help uncover the unique genetic contributions to kidney health in these populations. Ultimately, the goal is to improve understanding of CKD and inform future treatment strategies tailored to diverse ethnic groups.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from Hispanic/Latino backgrounds or other under-represented ethnic groups who are at risk for chronic kidney disease.
Not a fit: Patients who do not belong to the targeted ethnic groups or those without a family history of kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better risk assessment and personalized treatment options for chronic kidney disease in diverse populations.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for kidney disease in specific populations, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Franceschini, Nora — Univ of North Carolina Chapel Hill
- Study coordinator: Franceschini, Nora
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.