Understanding the genetics of kidney disease and high blood pressure

Genetic of Kidney Disease and Hypertension in MVP II

NIH-funded research Veterans Health Administration · NIH-10923318

This study is looking at how genes might affect chronic kidney disease and high blood pressure, especially in people of African descent, to help us better understand the disease and find ways to improve treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10923318 on NIH RePORTER

What this research studies

This research investigates the genetic factors contributing to chronic kidney disease (CKD) and hypertension, particularly in individuals of African descent. By analyzing kidney biopsy data and utilizing advanced techniques such as genomics and proteomics, the study aims to create a comprehensive model of CKD progression. This approach seeks to identify specific genetic markers and mechanisms that influence disease outcomes, ultimately improving our understanding of CKD and its management.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old, particularly those of African ancestry who are experiencing chronic kidney disease or hypertension.

Not a fit: Patients with kidney disease not of African descent or those without chronic kidney disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and personalized management strategies for patients with chronic kidney disease.

How similar studies have performed: Previous research has shown promise in understanding genetic contributions to kidney disease, but this study aims to provide a novel and comprehensive approach to CKD progression.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.