Understanding the genetics of high-grade gliomas
Functional Genomics of High Grade Glioma
This study is looking at glioblastoma, a tough type of brain cancer, to find out how its genes affect how it grows and resists treatment, and it also wants to understand how this cancer is linked to epilepsy, which many patients experience.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10895583 on NIH RePORTER |
What this research studies
This research investigates high-grade gliomas, particularly glioblastoma, which is a severe and often fatal brain cancer. By utilizing advanced genomic sequencing technologies, the study aims to uncover the underlying genetic factors that contribute to the disease's progression and treatment resistance. The researchers are developing innovative methods to analyze genetic information in a living model, allowing them to test multiple genetic factors simultaneously. Additionally, the research will explore the relationship between gliomas and epilepsy, a common complication in patients with this type of tumor.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with high-grade gliomas, particularly glioblastoma, and those experiencing glioma-associated epilepsy.
Not a fit: Patients with low-grade gliomas or other types of brain tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve outcomes for patients with high-grade gliomas.
How similar studies have performed: Previous research utilizing genomic approaches in cancer has shown promise, indicating potential for success in this novel application.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Yu, Kwanha — Baylor College of Medicine
- Study coordinator: Yu, Kwanha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.