Understanding the Genetics of Hair Pulling and Skin Picking
Neurogenomic Investigations of Trichotillomania and Excoriation Disorder
['FUNDING_CAREER'] · YALE UNIVERSITY · NIH-11116944
This research aims to understand the genetic causes of hair pulling (trichotillomania) and skin picking (excoriation disorder) to help find better ways to treat these conditions.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11116944 on ClinicalTrials.gov |
What this research studies
Many people struggle with hair pulling and skin picking, which are difficult to treat and currently lack effective medications. This project looks into the genetic factors that contribute to these behaviors, hoping to uncover the underlying biological pathways. By studying DNA from families affected by these conditions, and using advanced lab models of brain development, we hope to identify specific genes involved. This deeper understanding is a crucial step toward developing new and more effective treatments for those affected.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be individuals with trichotillomania or excoriation disorder, particularly those who can participate with their parents as a family trio.
Not a fit: Patients who do not have trichotillomania or excoriation disorder, or those not interested in genetic research, would not directly benefit from this specific study.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new genetic targets for medications, offering hope for more effective treatments for hair pulling and skin picking.
How similar studies have performed: While previous work suggests a genetic link for these behaviors, identifying specific risk genes has been challenging, making this approach a critical next step with promising preliminary data.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OLFSON, EMILY HUNT — YALE UNIVERSITY
- Study coordinator: OLFSON, EMILY HUNT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder