Understanding the genetics of frontotemporal lobar degeneration
Genetics Core
This study is looking at the genes of people with frontotemporal lobar degeneration (FTLD) and their family members to find out more about what might cause the disease, so we can better understand it and help with future research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10889903 on NIH RePORTER |
What this research studies
This research focuses on collecting and analyzing genetic data from patients with frontotemporal lobar degeneration (FTLD) and their blood relatives. By generating detailed genetic profiles, the study aims to identify genetic factors associated with FTLD, which can help in understanding the disease better. The research involves enrolling a large cohort of individuals, collecting DNA samples, and performing advanced genetic analyses to uncover potential causal mutations. This information will not only support ongoing FTLD research but also contribute to future gene discovery efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with frontotemporal lobar degeneration and their family members.
Not a fit: Patients with other types of dementia or neurological disorders unrelated to frontotemporal lobar degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential treatments for frontotemporal lobar degeneration.
How similar studies have performed: Previous research has shown success in genetic studies of neurodegenerative diseases, indicating that this approach is promising.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Rademakers, Rosa — Mayo Clinic Rochester
- Study coordinator: Rademakers, Rosa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.