Understanding the genetics behind heart disease in people with chronic kidney disease
Genetics of Cardiovascular Disease in Chronic Kidney Disease
This study is looking at how our genes might play a role in why people with chronic kidney disease often have heart problems, and it's for anyone interested in understanding how to improve heart health for those with kidney issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11077309 on NIH RePORTER |
What this research studies
This research investigates how genetic factors contribute to the higher rates of cardiovascular disease in individuals with chronic kidney disease (CKD). By analyzing data from the Chronic Renal Insufficiency Cohort, the study aims to identify specific genetic variants linked to cardiovascular outcomes. Researchers will utilize advanced techniques to integrate gene expression data with genetic information, focusing on diverse populations. The goal is to uncover new genetic insights that could lead to better prevention and treatment strategies for heart disease in CKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who have been diagnosed with chronic kidney disease.
Not a fit: Patients without chronic kidney disease or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular disease in patients with chronic kidney disease.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to cardiovascular disease, suggesting that this approach may yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Franceschini, Nora — Univ of North Carolina Chapel Hill
- Study coordinator: Franceschini, Nora
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.