Understanding the genetics and microbiome of the lone star tick

Integrating population genomics and microbial metagenomics of the lone star tick, an expanding arthropod disease vector

['FUNDING_R15'] · PEPPERDINE UNIVERSITY · NIH-10360088

This study is looking at the lone star tick to learn more about its genes and the germs it carries, which could help us understand how these ticks spread diseases, especially for people living in the Midwest and Northeast.

Quick facts

Phase['FUNDING_R15']
Study typeNih_funding
SexAll
SponsorPEPPERDINE UNIVERSITY (nih funded)
Locations1 site (MALIBU, UNITED STATES)
Trial IDNIH-10360088 on ClinicalTrials.gov

What this research studies

This research investigates the lone star tick, a significant disease vector, by examining its genetic makeup and the microorganisms it carries. The study aims to understand how the diversity in the tick's genome and its microbiome influences the tick's ability to transmit diseases. Using advanced DNA sequencing techniques, researchers will analyze tick populations in the Midwest and Northeast to identify patterns in genetic variation and pathogen prevalence. This work could provide insights into how environmental factors affect tick-borne diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living in or traveling to areas where lone star ticks are prevalent, particularly in the Midwest and Northeast regions of the United States.

Not a fit: Patients who do not reside in or travel to regions affected by lone star ticks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing and preventing tick-borne diseases.

How similar studies have performed: Other research has shown success in understanding tick-borne diseases through genomic and microbiome studies, indicating that this approach is promising.

Where this research is happening

MALIBU, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.