Understanding the genetics and biology of lung function and COPD
Integrative genomic, transcriptomic and proteomic studies of pulmonary function and COPD
This study is looking at how our genes and biology affect lung health and the progression of COPD, especially in people from diverse backgrounds, to help find better treatments tailored for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10897978 on NIH RePORTER |
What this research studies
This research investigates the genetic and biological factors that influence lung function and the progression of chronic obstructive pulmonary disease (COPD). By analyzing genomic, transcriptomic, and proteomic data from a diverse group of participants, including those of African American and Hispanic/Latino descent, the study aims to identify specific genetic variants associated with COPD. The approach includes large-scale data collection and analysis to better understand how these factors contribute to the disease, particularly in underrepresented populations. Patients may benefit from insights that could lead to more effective treatments and personalized medicine approaches for COPD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with COPD, particularly those from diverse ethnic backgrounds.
Not a fit: Patients without a diagnosis of COPD or those not from the targeted ethnic groups may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with COPD.
How similar studies have performed: Previous research has shown promise in understanding genetic factors in COPD, but this study aims to enhance representation and explore novel genetic variants.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Manichaikul, Ani Wang — University of Virginia
- Study coordinator: Manichaikul, Ani Wang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.