Understanding the genetic makeup of glioblastoma to improve treatment options
Molecular Profiling and Bioinformatics
This study is looking at how the genes in glioblastoma, a type of brain cancer, affect how well different treatments work, so that patients can get personalized information to help guide their treatment choices.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10928762 on NIH RePORTER |
What this research studies
This research focuses on using advanced genomic and bioinformatics techniques to analyze glioblastoma, a type of brain cancer. By providing comprehensive genomic profiling and sequencing, the project aims to identify specific genetic features that influence how tumors respond to various treatments. Patients enrolled in clinical trials will benefit from personalized insights that can guide their treatment decisions based on the unique characteristics of their tumors. The research also includes studying tumor samples to understand their evolution and resistance mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are eligible for clinical trials.
Not a fit: Patients with other types of brain tumors or those not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatment strategies for patients with glioblastoma.
How similar studies have performed: Previous research has shown promise in using genomic profiling to tailor cancer treatments, indicating that this approach could be beneficial.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Berens, Michael E. — Beckman Research Institute/city of Hope
- Study coordinator: Berens, Michael E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.