Understanding the genetic links between PTSD and substance use disorders.
Official title: Genetic Comorbidity of PTSD and Substance Use Disorders in Diverse Populations.
Funded at Suny Downstate Medical Center · NIH-10925228 · Data updated 2026-11-12
This study is looking into how our genes might link Posttraumatic Stress Disorder (PTSD) with issues like alcohol, cannabis, and opioid use, hoping to find helpful information that could lead to better ways to prevent and treat these conditions for people like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Suny Downstate Medical Center NIH-funded |
| Lab location | 1 site (Brooklyn, United States) |
| Project start | September 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $679,301 |
| NIH project number | 5R01DA060596-02 |
| Project ID | NIH-10925228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with PTSD who also have a history of substance use disorders.
✕Less likely to help
Patients who do not have PTSD or substance use disorders may not receive any benefit from this research.
What this research studies
This research investigates the genetic connections between Posttraumatic Stress Disorder (PTSD) and various Substance Use Disorders (SUD), such as alcohol, cannabis, and opioids. By utilizing advanced statistical genetics methods, the study aims to uncover the underlying genetic factors that contribute to the co-occurrence of these disorders. Patients may benefit from insights that could lead to improved prevention and treatment strategies tailored to their specific genetic profiles.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and interventions for individuals suffering from both PTSD and substance use disorders.
How similar studies have gone: Previous research has shown promising results in understanding the genetic correlations between PTSD and alcohol use disorder, indicating potential for success in this area.
Where this research is happening
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Suny Downstate Medical Center
Brooklyn, United States Active
Researchers
- Principal investigator: Meyers, Jacquelyn Leigh — Suny Downstate Medical Center
- Study coordinator: Meyers, Jacquelyn Leigh
Related research
Other NIH-funded projects on the same topics.
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Written Exposure Therapy for Veterans with PTSD and Substance Use Disorder (brief trauma treatment)
A brief trauma-focused therapy called Written Exposure Therapy is being studied to help veterans who have both PTSD and substance use disorders.
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Web-based training to treat PTSD and substance use together in Veterans
A web-based training resource helps VA clinicians learn how to provide integrated treatment for Veterans with both PTSD and substance use disorders.
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Genetics of PTSD and Substance Use in Diverse Populations
This grant investigates how genes influence PTSD and substance use disorders in diverse groups to improve prevention and treatment.
-
Using Written Exposure Therapy to help Veterans with PTSD and Substance Use Disorders
This study is looking at how helpful Written Exposure Therapy can be for Veterans dealing with both PTSD and substance use issues, especially for those in rural areas who might not have easy access to care, to see if it can make their treatment better and improve their quality of life.
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Online training for clinicians to deliver COPE, a combined PTSD and substance-use therapy
This project offers web training to teach VA clinicians how to deliver COPE, a combined Prolonged Exposure therapy for Veterans with PTSD and substance use problems.
-
Five-session written therapy for veterans with PTSD and substance use problems
This project uses a five-session written exposure therapy to help veterans with PTSD and substance use disorders reduce trauma symptoms and stay engaged in addiction care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.