Understanding the genetic links between multiple health conditions

Unravelling genetic basis of comorbidity using EHR-linked biobank data

NIH-funded research University of Pennsylvania · NIH-10687123

This study is looking at how different health conditions can work together and impact each other by analyzing health records and genetic information, with the goal of finding better ways to diagnose and treat patients who have multiple health issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10687123 on NIH RePORTER

What this research studies

This research investigates how different medical conditions can coexist and affect each other by analyzing large sets of health data linked to electronic health records. By utilizing advanced bioinformatics and clinical informatics techniques, the study aims to uncover the genetic factors that contribute to these comorbidities. Patients' health information, including genetic data, will be examined to identify patterns and associations that could lead to better diagnosis and treatment strategies. The goal is to enhance clinical decision-making for individuals facing multiple health challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with multiple chronic health conditions who are seeking better management of their health.

Not a fit: Patients with single, non-comorbid health conditions may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for patients with multiple health conditions, enhancing their overall care.

How similar studies have performed: Previous research has shown promise in using large-scale health data to understand comorbidities, indicating that this approach could yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.