Understanding the genetic history of South Asians and their microbes
Reconstructing the evolutionary history of humans and human-associated microbes in South Asia using an integrated genomics approach
['FUNDING_OTHER'] · UNIVERSITY OF CHICAGO · NIH-10877178
This study looks at the genetics and social backgrounds of South Asians to understand their history, how diseases have changed over time, and how diet affects gut health, which could help people learn more about their own health risks and the role of gut bacteria.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10877178 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic and social structures of South Asians, who make up a significant portion of the global population. By analyzing both ancient and modern genomic data, the project aims to uncover the demographic history of this region over the last 8,000 years, the evolution of infectious diseases, and how dietary changes have affected gut microbiome health. Patients may benefit from insights into genetic predispositions to diseases and the role of microbes in health. The research employs advanced genomic techniques to gather and analyze data from diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals of South Asian ancestry, particularly those with a history of infectious or non-infectious diseases.
Not a fit: Patients who do not have South Asian ancestry may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of disease susceptibility and health outcomes for South Asian populations.
How similar studies have performed: Previous research has shown success in using genomic approaches to understand population health and disease evolution, making this a promising area of study.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAGHAVAN, MAANASA — UNIVERSITY OF CHICAGO
- Study coordinator: RAGHAVAN, MAANASA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases