Understanding the genetic factors that influence the severity of endometriosis
Disentangling the genetic mechanisms of endometriosis severity with single-cell multi-omics
This study is looking at how genes might affect the severity of endometriosis, a painful condition many women experience, and it involves patients to help us learn more about the differences between mild and severe cases so we can improve treatment and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11176357 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms that contribute to the severity of endometriosis, a condition affecting many women of reproductive age. By utilizing advanced techniques such as single-cell epigenomics and multi-omics, the study aims to analyze gene regulation and identify genetic predictors of disease outcomes. Patients will be involved in a large cohort study that provides detailed clinical information, helping to uncover the biological differences between low and high stages of endometriosis. The findings could lead to better understanding and management of this painful condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are women of reproductive age who have been diagnosed with endometriosis.
Not a fit: Patients who do not have endometriosis or are outside the reproductive age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and personalized treatment options for women suffering from endometriosis.
How similar studies have performed: Previous research has shown promise in understanding genetic factors in other chronic conditions, suggesting potential for success in this novel approach to endometriosis.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Lawrenson, Kate — University of Texas Hlth Science Center
- Study coordinator: Lawrenson, Kate
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.