Understanding the genetic factors that increase the risk of pancreatic cancer in diverse populations.
Multi-Ancestry Mapping of Pancreatic Cancer Susceptibility Loci
This study is looking at the genes of African Americans with pancreatic cancer to find out why they are more affected by this disease, hoping to discover new ways to prevent and treat it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11065435 on NIH RePORTER |
What this research studies
This research aims to uncover the genetic basis of pancreatic cancer, particularly focusing on African Americans who are disproportionately affected by this disease. By conducting whole genome sequencing, the study will analyze genetic data from African American pancreatic cancer patients and healthy controls. The goal is to identify specific genetic markers that contribute to the risk of developing pancreatic cancer, which could lead to better prevention and treatment strategies. This research addresses a significant gap in knowledge, as previous studies have not adequately included diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals diagnosed with pancreatic cancer or those without the disease who are willing to participate.
Not a fit: Patients of other ethnic backgrounds or those without a family history of pancreatic cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted prevention strategies for pancreatic cancer in African American populations.
How similar studies have performed: While there have been successful genetic studies in other cancer types, this specific focus on pancreatic cancer in African Americans is novel and has not been extensively explored.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Klein, Alison P — Johns Hopkins University
- Study coordinator: Klein, Alison P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.