Understanding the genetic factors that contribute to Alzheimer's disease risk
Cognitive Computing of Alzheimer's Disease Genes and Risk
This study is looking at how certain genes might increase the risk of Alzheimer's disease, using advanced computer techniques to help find these genetic clues, which could lead to better ways to identify and prevent the disease for those at risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10885031 on NIH RePORTER |
What this research studies
This research investigates the complex genetic architecture of Alzheimer's disease (AD) by utilizing cognitive computing techniques to analyze genetic data. It aims to identify specific genetic mutations that contribute to AD risk and improve the accuracy of patient classifications. By integrating vast amounts of genetic information and conducting rigorous experimental validation, the research seeks to enhance our understanding of how these mutations affect disease progression. This could ultimately lead to better screening and prevention strategies for individuals at risk of developing Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's disease or those who are genetically predisposed to the condition.
Not a fit: Patients who do not have any genetic risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective screening and prevention strategies for Alzheimer's disease, potentially delaying or reducing the incidence of the condition.
How similar studies have performed: Previous research has shown promise in using genetic analysis to identify risk factors for Alzheimer's disease, indicating that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Lichtarge, Olivier — Baylor College of Medicine
- Study coordinator: Lichtarge, Olivier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.