Understanding the genetic factors related to tauopathy risk and protection.
Core A: Administrative
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10906035
This study is looking at how certain genes might affect the risk of tauopathy, a brain disease, and it's for anyone interested in understanding how our genetics can help us find better ways to prevent and treat this condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10906035 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying and validating the molecular mechanisms that contribute to the risk and protection of tauopathy, a type of neurodegenerative disease, associated with specific genetic haplotypes. The project involves collaboration among three major research sites in New York, Los Angeles, and San Francisco, facilitating communication and resource sharing among scientists. By connecting these sites, the research aims to enhance the understanding of how genetic factors influence tauopathy, which could lead to better prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of tauopathy or those identified as having the H1/H2 haplotypes associated with increased risk.
Not a fit: Patients who do not have a genetic predisposition to tauopathy or those without a family history of related neurodegenerative diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for individuals at risk of tauopathy.
How similar studies have performed: Previous research has shown promise in understanding genetic factors related to neurodegenerative diseases, indicating that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOATE, ALISON M — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: GOATE, ALISON M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.