Understanding the genetic factors of non-alcoholic fatty liver disease

Integrative Polygenic Genetic Studies of Non-alcoholic Fatty Liver Disease

NIH-funded research University of Michigan at Ann Arbor · NIH-11083752

This study is looking at how our genes might play a role in non-alcoholic fatty liver disease (NAFLD) to help find better ways to diagnose and treat it for people who have this condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11083752 on NIH RePORTER

What this research studies

This research investigates the genetic basis of non-alcoholic fatty liver disease (NAFLD), which affects millions of adults in the U.S. The study aims to identify genetic variants that contribute to the disease and its progression, using advanced genetic analysis techniques. By analyzing a diverse group of participants, researchers hope to uncover new insights into how genetics influence liver health and disease outcomes. This could lead to improved diagnostic tools and treatment options for those affected by NAFLD.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults with non-alcoholic fatty liver disease or those at risk due to genetic factors.

Not a fit: Patients without non-alcoholic fatty liver disease or those who do not have a genetic predisposition to liver conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention and treatment strategies for non-alcoholic fatty liver disease.

How similar studies have performed: Previous research has successfully identified genetic variants associated with liver diseases, suggesting that this approach has the potential for significant findings.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.