Understanding the genetic factors of Grade C Periodontitis in young people
Susceptibility Patterns for Grade C Periodontitis in Young Individuals
This study is looking at what causes a specific type of gum disease called Grade C Periodontitis in young people, so we can better understand it and help those who are affected.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10916561 on NIH RePORTER |
What this research studies
This research investigates the genetic and environmental factors that contribute to Grade C Periodontitis, particularly in young individuals. It focuses on a specific form of the disease known as Stage 3-4 Grade C, molar-incisor pattern periodontitis, which can lead to significant health issues if not diagnosed and treated early. The research team aims to identify genetic susceptibility variants and understand how different populations may be affected by this condition. By analyzing large cohorts, the study seeks to uncover the underlying causes of this disease and improve diagnosis and treatment options for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are young individuals, particularly those from low socioeconomic backgrounds, who are at risk for or diagnosed with Grade C Periodontitis.
Not a fit: Patients who do not have Grade C Periodontitis or are not within the targeted age group may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for young individuals suffering from Grade C Periodontitis.
How similar studies have performed: Previous research has shown promising results in identifying genetic factors related to periodontitis, but this specific focus on Grade C Periodontitis in young individuals is relatively novel.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Shaddox, Luciana Macchion — University of Kentucky
- Study coordinator: Shaddox, Luciana Macchion
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.