Understanding the genetic factors of endometriosis in diverse women
Official title: Functional Genomics Across an Ethnically and Racially Diverse Endometriosis Population
Funded at University of Texas Hlth Science Center · NIH-11004255 · Data updated 2026-11-12
This study is looking at the genetic changes linked to endometriosis in women from different backgrounds to find out how these changes might help improve treatment options for the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | July 16, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $558,588 |
| NIH project number | 5R01HD113693-03 |
| Project ID | NIH-11004255 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include reproductive-age women diagnosed with endometriosis, particularly those from diverse ethnic backgrounds.
✕Less likely to help
Patients who do not have endometriosis or are outside the reproductive age range may not benefit from this research.
What this research studies
This research investigates the genetic mutations associated with endometriosis in women from various ethnic backgrounds, including White, Asian, Black, and Hispanic populations. By analyzing over 1,400 patient specimens, the study aims to identify specific somatic mutations that contribute to the condition and explore their implications for treatment. Utilizing advanced genomic technologies, the research will map the frequency of these mutations and their effects on endometriosis and related tissues. This comprehensive approach seeks to uncover potential therapeutic targets that could improve care for affected women.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for women suffering from endometriosis.
How similar studies have gone: Previous research has shown promise in understanding genetic factors in endometriosis, but this study aims to provide novel insights by focusing on a diverse population.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Lawrenson, Kate — University of Texas Hlth Science Center
- Study coordinator: Lawrenson, Kate
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.