Understanding the genetic factors in gastrointestinal stromal tumors
Defining clinically relevant transcriptional networks in gastrointestinal stromal tumor
['FUNDING_CAREER'] · UNIV OF MASSACHUSETTS MED SCH WORCESTER · NIH-10891388
This study is looking at the genes and signals that affect gastrointestinal stromal tumors (GIST) to help understand how they behave and what might predict how well patients do after treatment, with the hope of finding better ways to manage the disease for each person.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MASSACHUSETTS MED SCH WORCESTER (nih funded) |
| Locations | 1 site (WORCESTER, UNITED STATES) |
| Trial ID | NIH-10891388 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic and transcriptional networks involved in gastrointestinal stromal tumors (GIST), a type of soft tissue sarcoma. By analyzing the transcription factors and their interactions, the study aims to identify key elements that predict patient outcomes and disease behavior. The researchers will explore how these genetic factors influence the progression of the disease and the risk of recurrence after treatment. This work could lead to improved strategies for managing GIST and tailoring therapies to individual patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with gastrointestinal stromal tumors, particularly those facing uncertainties regarding their disease progression.
Not a fit: Patients with other types of cancers or those without a diagnosis of gastrointestinal stromal tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better predictions of disease outcomes and more personalized treatment options for patients with GIST.
How similar studies have performed: Previous research has shown promise in understanding transcriptional networks in other cancers, suggesting that this approach could yield valuable insights for GIST as well.
Where this research is happening
WORCESTER, UNITED STATES
- UNIV OF MASSACHUSETTS MED SCH WORCESTER — WORCESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEMMING, MATTHEW — UNIV OF MASSACHUSETTS MED SCH WORCESTER
- Study coordinator: HEMMING, MATTHEW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers