Understanding the genetic factors behind substance use disorder
Statistical methods for gene regulatory analysis of substance use disorder
['FUNDING_R21'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-11262563
This study is looking at how genes and the environment work together to affect substance use disorder, and it aims to find new ways to help people struggling with addiction by analyzing brain samples from both humans and fruit flies.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-11262563 on ClinicalTrials.gov |
What this research studies
This research investigates the complex genetic and environmental factors that contribute to substance use disorder (SUD). By developing advanced statistical methods and bioinformatics tools, the project aims to analyze data from both human and Drosophila brain samples to identify specific cells and genetic variations linked to addiction. The approach integrates various data types, including genome-wide association studies, to create a comprehensive understanding of how these factors interact and influence addiction. Patients may benefit from insights that could lead to more effective therapies for SUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of substance use disorder or those at risk of developing such conditions.
Not a fit: Patients who do not have a substance use disorder or are not at risk for addiction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more targeted and effective treatments for substance use disorders.
How similar studies have performed: Previous research has shown promise in using genetic and bioinformatics approaches to understand addiction, indicating that this methodology could yield valuable insights.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUREN, ZHANA — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: DUREN, ZHANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder