Understanding the genetic factors behind problematic alcohol use
The development of genetically-based pathways underlying problematic alcohol use
This study is looking at how genetics might play a role in alcohol problems among teens and young adults, especially focusing on traits like conduct issues and depression that can lead to these challenges, with the goal of finding better ways to prevent and treat alcohol use disorders.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10854985 on NIH RePORTER |
What this research studies
This research investigates the genetic pathways that contribute to problematic alcohol use, particularly focusing on adolescents and young adults. By analyzing data from multiple long-term studies, the research aims to identify heritable traits linked to conduct problems and depression, which are precursors to alcohol use disorders. The study will utilize advanced data harmonization techniques to integrate findings from various cohorts, allowing for a comprehensive understanding of how these traits are inherited and their impact on alcohol consumption behaviors. This approach seeks to develop more precise prevention and treatment strategies for alcohol use disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who exhibit symptoms of conduct problems or depression.
Not a fit: Patients who do not have a history of alcohol use or related behavioral issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for individuals at risk of problematic alcohol use.
How similar studies have performed: Previous research has shown promise in understanding genetic factors related to alcohol use, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Wang, Frances L — University of Pittsburgh at Pittsburgh
- Study coordinator: Wang, Frances L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.