Understanding the genetic factors behind fentanyl and cocaine addiction
Dissecting the shared genetic mechanisms driving fentanyl addiction, cocaine addiction, and incentive sensitization using the Collaborative Cross mouse panel
This study is looking at how our genes might play a role in addiction to fentanyl and cocaine, using mice to see how different genetic traits affect behavior, with the hope of finding new ways to help people who are dealing with these addictions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marshall University NIH-funded |
| Lab location | 1 site (Huntington, UNITED STATES) |
| Project ID | NIH-11095855 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms that contribute to addiction to fentanyl and cocaine, focusing on how these substances affect brain reward systems. By using a special panel of mice that represent a wide range of genetic diversity, researchers will explore how genetic variations influence behaviors associated with addiction. The study employs advanced techniques, including behavioral tests and neurophysiology assays, to uncover the underlying genetic drivers of addiction. The ultimate goal is to identify potential targets for new treatments that could help individuals struggling with these addictions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are struggling with addiction to cocaine or fentanyl.
Not a fit: Patients who are not addicted to cocaine or fentanyl, or those under 21 years old, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating fentanyl and cocaine addiction.
How similar studies have performed: Previous research has shown success in identifying genetic factors related to addiction, suggesting that this approach could yield valuable insights.
Where this research is happening
Huntington, UNITED STATES
- Marshall University — Huntington, United States (Active)
Researchers
- Principal investigator: Dickson, Price Evans — Marshall University
- Study coordinator: Dickson, Price Evans
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.