Understanding the genetic factors behind complex diseases and traits
Resolving and understanding the genomic basis of heterogeneous complex traits and disease
This study is looking at how our genes can influence complex diseases and traits, helping us understand how these differences affect our bodies, so we can find better ways to diagnose and treat people of all ages and genders who are dealing with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10700497 on NIH RePORTER |
What this research studies
This research investigates the genetic variations that contribute to complex diseases and traits by analyzing how these variations affect cellular processes and tissue function. The team employs advanced computational methods to identify and categorize subtypes of diseases based on shared characteristics, as well as to explore differences in disease prevalence and impact between genders and across different ages. By bridging gaps in our understanding of these relationships, the research aims to improve disease diagnosis and treatment strategies for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with complex diseases such as coronary artery disease, gastrointestinal disorders, or those experiencing significant variations in disease symptoms based on age or gender.
Not a fit: Patients with well-defined single-gene disorders or those not affected by complex traits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnoses and targeted treatments for complex diseases, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding complex traits through genomic studies, indicating that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Krishnan, Arjun — University of Colorado Denver
- Study coordinator: Krishnan, Arjun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.