Understanding the genetic factors behind atrial fibrillation
Probing Phenotype-Genotype Relations After Whole Genome Sequencing in Patients with Atrial Fibrillation
This study is looking at how your genes might play a role in atrial fibrillation, a common heart rhythm problem, to help find ways to spot and treat it earlier for people who might be at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10899642 on NIH RePORTER |
What this research studies
This research investigates how genetic factors contribute to atrial fibrillation (AF), a common heart rhythm disorder. By utilizing whole genome sequencing, the study aims to identify patients who may have underlying genetic conditions that could lead to serious heart issues. Participants will be part of a large cohort, allowing researchers to analyze genetic data alongside clinical information to better understand the relationship between genetics and AF. The goal is to improve early detection and treatment strategies for individuals at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 60 years old who have been diagnosed with atrial fibrillation.
Not a fit: Patients with atrial fibrillation who are over 60 years old or do not have a genetic predisposition to heart conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of atrial fibrillation and related genetic heart conditions.
How similar studies have performed: Previous research has shown promising results in understanding genetic contributions to cardiovascular diseases using similar genomic approaches.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Shoemaker, Moore Benjamin — Vanderbilt University Medical Center
- Study coordinator: Shoemaker, Moore Benjamin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.