Understanding the genetic factors behind allergies in children
A single cell pooling framework for deciphering the regulatory wiring of allergy in pathophysiologic contexts
This study is looking into what causes peanut allergies in kids by exploring both their genes and the environment, hoping to find new ways to prevent and treat these allergies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11062710 on NIH RePORTER |
What this research studies
This research investigates the complex genetic and environmental factors that contribute to allergies, particularly focusing on peanut allergies in children. By utilizing a single cell pooling framework, the study aims to identify the regulatory mechanisms that influence gene expression related to allergies. The approach involves analyzing genetic data from a diverse population to uncover the underlying causes of allergic reactions. Patients may benefit from insights that could lead to improved prevention and treatment strategies for allergies.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 years who have been diagnosed with allergies, particularly peanut allergies.
Not a fit: Patients who do not have allergies or are older than 11 years may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of allergies, potentially reducing their incidence and severity in children.
How similar studies have performed: Previous research has shown success in identifying genetic factors associated with allergies, but this approach aims to provide a more comprehensive understanding of regulatory mechanisms, making it a novel effort.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kasowski, Maya — Stanford University
- Study coordinator: Kasowski, Maya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.