Understanding the genetic differences in multiple myeloma among racial groups
Mutographs differentiating the racial and temporal incidence of multiple myeloma
This study is looking at how genetics might explain why multiple myeloma is more common in African Americans than in European Americans, with the hope that the findings will help create better ways to prevent and treat the disease for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10905016 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to the higher incidence of multiple myeloma in African Americans compared to European Americans. By analyzing genetic mutations over time, the study aims to identify unique mutational signatures that may explain the increased risk and progression of the disease in different racial groups. Patients may benefit from insights into the early stages of multiple myeloma, which could lead to improved prevention and treatment strategies tailored to their genetic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for this research include African American individuals who are at risk for or diagnosed with multiple myeloma or its precursor conditions.
Not a fit: Patients of other racial backgrounds who do not have multiple myeloma or its precursor conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of multiple myeloma, particularly for African American patients who are at higher risk.
How similar studies have performed: Previous research has shown success in identifying genetic factors influencing multiple myeloma, but this study aims to provide novel insights specific to racial differences.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Morgan, Gareth John — New York University School of Medicine
- Study coordinator: Morgan, Gareth John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.