Understanding the genetic causes of temporal lobe epilepsy
Genetic and Cellular Mechanisms of Temporal Lobe Epilepsy
This study is looking into how certain genes and cells might play a role in temporal lobe epilepsy, and it's designed for people interested in understanding the genetic factors that could affect brain function and contribute to this condition.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11075784 on NIH RePORTER |
What this research studies
This research focuses on exploring the genetic and cellular mechanisms that contribute to temporal lobe epilepsy. The principal investigator, Dr. Khoshkhoo, will receive specialized training in human genetics and advanced sequencing techniques to analyze genetic variants associated with this condition. By studying these genetic factors, the research aims to uncover how specific mutations affect brain function and contribute to epilepsy. This work is supported by leading institutions in Boston, providing a robust environment for scientific discovery.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with temporal lobe epilepsy, particularly those with a family history of the condition or unexplained seizures.
Not a fit: Patients with epilepsy caused by non-genetic factors or those who do not have temporal lobe epilepsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with temporal lobe epilepsy.
How similar studies have performed: Previous research in epilepsy genetics has shown promise in identifying genetic factors, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Khoshkhoo, Sattar — Brigham and Women's Hospital
- Study coordinator: Khoshkhoo, Sattar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.