Understanding the genetic causes of Polycystic Ovary Syndrome
Genetic Dissection of the Pathophysiology of Polycystic Ovary Syndrome
['FUNDING_CAREER'] · BOSTON CHILDREN'S HOSPITAL · NIH-10886797
This study is looking at the genes that might play a role in Polycystic Ovary Syndrome (PCOS) to help us understand why it happens and how it affects not just women, but also men and children, with the hope of finding better ways to address the condition beyond just treating the symptoms.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10886797 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic factors contributing to Polycystic Ovary Syndrome (PCOS), a condition affecting many reproductive-aged women and leading to infertility. By analyzing genetic data from a large-scale study, the project aims to identify how various metabolic and reproductive pathways are altered in individuals with PCOS. The research will explore these genetic influences not only in women but also in men and children, providing a broader understanding of the condition. This comprehensive approach may lead to new insights into the underlying causes of PCOS, moving beyond just symptom management.
Who could benefit from this research
Good fit: Ideal candidates for this research include women of reproductive age diagnosed with PCOS, as well as men and children who may be affected by related metabolic and reproductive issues.
Not a fit: Patients who do not have PCOS or related endocrine disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments targeting the root causes of PCOS rather than just its symptoms.
How similar studies have performed: Previous research has shown promise in understanding genetic factors in similar endocrine disorders, suggesting potential for success in this novel approach to PCOS.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHU, JIA — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: ZHU, JIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiometabolic Disease