Understanding the genetic causes of intellectual disability in diverse families
Elucidating the Genetic Etiology of Intellectual Disability in African, Asian, and European Families
This study is looking at the genes of families from different backgrounds to find out what might cause intellectual disability, hoping to help improve diagnosis and treatment for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906931 on NIH RePORTER |
What this research studies
This research aims to identify the genetic factors that contribute to intellectual disability (ID) in families from African, Asian, and European backgrounds. By analyzing DNA samples from affected individuals and their parents, the study will utilize next-generation sequencing to uncover genetic variants associated with ID. The research will focus on families with a history of ID, excluding those with specific known causes, to better understand the genetic landscape of this condition. The findings could lead to improved diagnostic methods and potential treatments for individuals with ID.
Who could benefit from this research
Good fit: Ideal candidates for this research are families with a member diagnosed with intellectual disability, particularly those from African, Asian, or European backgrounds.
Not a fit: Patients with intellectual disability caused by known factors such as Fragile X syndrome or environmental exposures will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the understanding of intellectual disability and lead to better diagnostic and treatment options for affected individuals.
How similar studies have performed: Previous research has successfully identified genetic variants associated with intellectual disability in various populations, indicating that this approach has potential for meaningful discoveries.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Leal, Suzanne M — Columbia University Health Sciences
- Study coordinator: Leal, Suzanne M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.