Understanding the genetic causes of human sleep disorders related to circadian rhythms
Molecular mechanisms underlying human circadian sleep disorders
This study is looking at how certain genetic differences might affect sleep problems related to our body’s natural clock, with the hope of finding new ways to help people who struggle with sleep issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project ID | NIH-10474631 on NIH RePORTER |
What this research studies
This research investigates how genetic variations affect circadian sleep disorders, which can lead to poor sleep quality and increased health risks. By studying a diverse set of genetic mutations and single-nucleotide polymorphisms (SNPs), the research aims to improve our understanding of how these variations influence sleep patterns. The team has developed new animal models that mimic unstable sleep-wake cycles, allowing for a better exploration of these disorders. Ultimately, the goal is to identify potential genetic targets for developing effective treatments for those affected by circadian rhythm disruptions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing circadian sleep disorders, particularly those with unpredictable sleep-wake cycles.
Not a fit: Patients with sleep disorders not related to circadian rhythms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for individuals suffering from circadian sleep disorders, improving their sleep quality and overall health.
How similar studies have performed: Previous research has shown promise in understanding genetic influences on sleep disorders, but this approach is innovative in its focus on a diverse range of genetic variations.
Where this research is happening
Tallahassee, United States
- Florida State University — Tallahassee, United States (Active)
Researchers
- Principal investigator: Lee, Choogon — Florida State University
- Study coordinator: Lee, Choogon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.