Understanding the genetic causes of hearing loss as people age
The genetic basis for age-related hearing loss in outbred mice
This study is looking at how our genes might affect hearing loss as we get older, using mice to help find out which specific genes are involved, with the hope that this could lead to better treatments for people experiencing hearing loss.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10906860 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to age-related hearing impairment (ARHI) using outbred mice as a model. By examining the genetic makeup of these mice, researchers aim to identify specific genes associated with hearing loss that occurs as individuals age. The study utilizes advanced genetic techniques and auditory assessments to explore the relationship between genetics and hearing function. Insights gained from this research could lead to better understanding and potential treatments for hearing loss in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those over the age of 70, who are experiencing hearing loss.
Not a fit: Patients with hearing loss due to non-genetic factors or those under the age of 70 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related hearing loss in patients.
How similar studies have performed: Previous research has shown success in identifying genetic factors related to hearing loss, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Friedman, Rick a — University of California, San Diego
- Study coordinator: Friedman, Rick a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.