Understanding the genetic causes of early-onset atrial fibrillation
Official title: Investigating structural and genetic substrates of early-onset atrial fibrillation
Funded at Lurie Children's Hospital of Chicago · NIH-10843185 · Data updated 2026-11-12
This study is looking at the genes and other factors that might cause young people under 35 to have atrial fibrillation, and it hopes to find clues that can help doctors create better treatment plans for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $499,842 |
| NIH project number | 5R01HL164773-02 |
| Project ID | NIH-10843185 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 35 or younger who have experienced their first episode of atrial fibrillation.
✕Less likely to help
Patients who are older than 35 years or those without a history of atrial fibrillation may not benefit from this research.
What this research studies
This research investigates the genetic and structural factors that contribute to early-onset atrial fibrillation, which occurs in individuals under 35 years of age. The study aims to identify specific genetic markers that may predict the recurrence of this condition in young patients. By utilizing advanced genomic techniques, researchers will collect genetic material and clinical data from participants to better understand how these factors influence the frequency of atrial fibrillation episodes. The goal is to develop more effective treatment recommendations tailored for younger patients suffering from this arrhythmia.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for young patients with early-onset atrial fibrillation, potentially reducing the frequency of their arrhythmia episodes.
How similar studies have gone: Previous research has shown that genetic factors play a significant role in arrhythmias, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Webster, Robert Gregory — Lurie Children's Hospital of Chicago
- Study coordinator: Webster, Robert Gregory
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.