NIH-funded research R01 grant

Understanding the genetic causes of ADHD in families

Official title: Advancing Understanding of Genomic Mechanisms for Primary ADHD in Families

Funded at Boston Children's Hospital · NIH-11145234 · Data updated 2026-11-12

This study is looking at the genetic factors that might cause ADHD in kids aged 0-11, and it’s for families with children who have ADHD to help us learn more about how this condition runs in families.

More ADHD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston Children's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 1, 2024
Project endApril 30, 2029
Funding year2025
Award (this year)$755,902
NIH project number5R01MH137118-02
Project IDNIH-11145234 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years diagnosed with primary ADHD and their family members.

Less likely to help

Patients with ADHD who also have significant comorbid conditions, such as severe intellectual disability or autism, may not benefit from this research.

What this research studies

This research investigates the genetic mechanisms behind primary ADHD, particularly in children aged 0-11 years. It aims to create a comprehensive family-based repository that includes children with ADHD and their family members, using standardized diagnostic criteria to ensure accurate ADHD diagnoses. By analyzing genomic data, the research seeks to identify rare genetic variants that may contribute to ADHD, enhancing our understanding of this condition and its familial patterns.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and targeted treatments for children with primary ADHD.

How similar studies have gone: Previous research has shown promise in understanding genetic factors in ADHD, but this approach aims to provide a more focused and comprehensive analysis of primary ADHD, making it a novel endeavor.

Where this research is happening

  • Boston Children's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Doan, Ryan Neil — Boston Children's Hospital
  • Study coordinator: Doan, Ryan Neil

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.