Understanding the genetic basis of endometriosis
Comparative Genomics and Bioinformatics Core
This study is looking at the genes and biological information related to endometriosis in women, comparing data from humans and animals to find important pathways and genes that could help us understand the condition better and improve future treatments.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10925406 on NIH RePORTER |
What this research studies
This research focuses on analyzing genetic and bioinformatic data to better understand the disease mechanisms of endometriosis in women. By comparing genomic features across humans, monkeys, and mice, the study aims to identify key pathways and genes involved in the disease. The research employs advanced techniques such as transcriptomics and epigenomics to integrate various types of biological data, which will help prioritize the most relevant pathways for further investigation. Ultimately, this work seeks to enhance our understanding of endometriosis and inform future treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with endometriosis or those experiencing difficulty conceiving.
Not a fit: Patients without a diagnosis of endometriosis or related reproductive disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic options for women suffering from endometriosis.
How similar studies have performed: Previous research using comparative genomics has shown promise in understanding complex diseases, suggesting that this approach could yield valuable insights into endometriosis.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Cox, Laura a — Duke University
- Study coordinator: Cox, Laura a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.