Understanding the genetic and molecular causes of heart disease
Official title: Genetic and Molecular Mechanisms of Heart Disease
Funded at University of Iowa · NIH-11035775 · Data updated 2026-11-12
This study is looking at how certain genes and tiny molecules in the body affect heart health, especially for people dealing with heart failure, to find new ways to improve diagnosis and treatment for heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | April 15, 2025 |
| Project end | January 31, 2032 |
| Funding year | 2025 |
| Award (this year) | $1,088,500 |
| NIH project number | 1R35HL177241-01 |
| Project ID | NIH-11035775 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with diagnosed heart conditions such as heart failure, cardiomyopathy, or arrhythmias.
✕Less likely to help
Patients without any cardiovascular issues or those with non-cardiac related health problems may not benefit from this research.
What this research studies
This research investigates the genetic and molecular mechanisms that contribute to heart disease, particularly focusing on heart failure and its associated complications. The team will explore how microRNAs and specific genetic variations affect heart function and contribute to conditions like cardiomyopathy and arrhythmias. By utilizing advanced techniques to analyze heart tissues, they aim to identify critical interactions that could lead to new therapeutic targets. Patients may benefit from insights that could improve diagnosis and treatment options for heart-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and preventive strategies for heart disease.
How similar studies have gone: Previous research has shown promise in understanding microRNA roles in heart disease, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Boudreau, Ryan L — University of Iowa
- Study coordinator: Boudreau, Ryan L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.