Understanding the genetic and molecular causes of heart disease

Genetic and Molecular Mechanisms of Heart Disease

['FUNDING_OTHER'] · UNIVERSITY OF IOWA · NIH-11035775

This study is looking at how certain genes and tiny molecules in the body affect heart health, especially for people dealing with heart failure, to find new ways to improve diagnosis and treatment for heart problems.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF IOWA (nih funded)
Locations1 site (IOWA CITY, UNITED STATES)
Trial IDNIH-11035775 on ClinicalTrials.gov

What this research studies

This research investigates the genetic and molecular mechanisms that contribute to heart disease, particularly focusing on heart failure and its associated complications. The team will explore how microRNAs and specific genetic variations affect heart function and contribute to conditions like cardiomyopathy and arrhythmias. By utilizing advanced techniques to analyze heart tissues, they aim to identify critical interactions that could lead to new therapeutic targets. Patients may benefit from insights that could improve diagnosis and treatment options for heart-related conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with diagnosed heart conditions such as heart failure, cardiomyopathy, or arrhythmias.

Not a fit: Patients without any cardiovascular issues or those with non-cardiac related health problems may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and preventive strategies for heart disease.

How similar studies have performed: Previous research has shown promise in understanding microRNA roles in heart disease, indicating that this approach could yield valuable insights.

Where this research is happening

IOWA CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cardiac Diseases, Cardiac Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.