Understanding the genetic and environmental factors that influence Alzheimer's disease and related conditions
Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic context
This study is looking into what causes Alzheimer's disease and related dementias by exploring both genetic and lifestyle factors, so we can better understand the disease and create personalized treatment plans for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10831558 on NIH RePORTER |
What this research studies
This research investigates the complex causes of Alzheimer's disease (AD) and related dementias by examining both genetic and non-genetic factors. It aims to identify specific risk profiles that can help tailor interventions to individual patients based on their unique predispositions. The study utilizes a variety of advanced methods to analyze how different factors interact and contribute to the development of AD and vascular diseases. By capturing this complexity, the research seeks to improve our understanding of the disease and enhance treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients with confirmed Alzheimer's disease who are already receiving treatment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective interventions for individuals at risk of Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in understanding the genetic and environmental factors of Alzheimer's disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Yashin, Anatoliy I — Duke University
- Study coordinator: Yashin, Anatoliy I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.