Understanding the genetic and brain factors behind ADHD in children

Leveraging computational strategies to disentangle the genetic and neural underpinnings of ADHD and its associated cognitive systems

NIH-funded research Massachusetts General Hospital · NIH-10925375

This study is looking at how genes and brain function affect ADHD in kids and how it relates to their thinking skills, with the goal of finding better ways to diagnose and treat children with ADHD.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10925375 on NIH RePORTER

What this research studies

This research investigates how genetic and neural factors contribute to attention deficit hyperactivity disorder (ADHD) and its impact on cognitive functions in children. By utilizing advanced computational strategies, the study aims to identify the complex relationships between cognitive impairments and ADHD symptoms. The research will involve analyzing data from various sources to better understand the heritable neurobiology of ADHD and its associated cognitive systems, ultimately aiming to improve diagnosis and treatment options for affected youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with ADHD or exhibit symptoms of the disorder.

Not a fit: Patients who do not have ADHD or are outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective interventions and support for children with ADHD, enhancing their cognitive functioning and overall quality of life.

How similar studies have performed: Previous research has shown promise in understanding cognitive impairments in ADHD, but this approach aims to provide novel insights into the genetic and neural underpinnings of the disorder.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.