Understanding the genetic and brain factors behind ADHD in children
Official title: Leveraging computational strategies to disentangle the genetic and neural underpinnings of ADHD and its associated cognitive systems
Funded at Massachusetts General Hospital · NIH-10925375 · Data updated 2026-11-12
This study is looking at how genes and brain function affect ADHD in kids and how it relates to their thinking skills, with the goal of finding better ways to diagnose and treat children with ADHD.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 8, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $732,244 |
| NIH project number | 5R01MH130899-02 |
| Project ID | NIH-10925375 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been diagnosed with ADHD or exhibit symptoms of the disorder.
✕Less likely to help
Patients who do not have ADHD or are outside the age range of 0-11 years may not benefit from this research.
What this research studies
This research investigates how genetic and neural factors contribute to attention deficit hyperactivity disorder (ADHD) and its impact on cognitive functions in children. By utilizing advanced computational strategies, the study aims to identify the complex relationships between cognitive impairments and ADHD symptoms. The research will involve analyzing data from various sources to better understand the heritable neurobiology of ADHD and its associated cognitive systems, ultimately aiming to improve diagnosis and treatment options for affected youth.
Why it matters
Potential benefit: If successful, this research could lead to more effective interventions and support for children with ADHD, enhancing their cognitive functioning and overall quality of life.
How similar studies have gone: Previous research has shown promise in understanding cognitive impairments in ADHD, but this approach aims to provide novel insights into the genetic and neural underpinnings of the disorder.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Ge, Tian — Massachusetts General Hospital
- Study coordinator: Ge, Tian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.