Understanding the genes that affect skin and eye color
Molecular Determinants of Pigmentation (MDoP)
This study is looking at the genes that affect skin and eye color, especially for kids with albinism who may have vision problems, to help find new ways to treat and prevent these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10884205 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to pigmentation in humans, particularly focusing on conditions like albinism that can lead to vision impairment in children. By identifying and characterizing new genes and proteins involved in pigmentation development and melanosome function, the study aims to fill gaps in our understanding of these disorders. The approach includes analyzing genetic mutations and their effects on melanin production and transportation, which are crucial for normal pigmentation. Ultimately, the research seeks to develop therapeutic strategies for treating and preventing pigmentation disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with albinism or other pigmentation disorders, particularly children who may experience vision impairment.
Not a fit: Patients without pigmentation disorders or those whose conditions are unrelated to genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for pigmentation disorders, improving vision and quality of life for affected individuals.
How similar studies have performed: Previous research has successfully identified genetic factors related to pigmentation, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Ahmed, Zubair M. — University of Maryland Baltimore
- Study coordinator: Ahmed, Zubair M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.