Understanding the factors that keep HIV hidden in the body
Cellular and viral determinants of the persistent HIV reservoir
This study is looking at what helps HIV hide in the body so we can find better ways to get rid of it, and it invites patients to share samples to help create tests that spot these hidden HIV-infected cells.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-10948094 on NIH RePORTER |
What this research studies
This research focuses on identifying the specific cellular and viral factors that contribute to the persistence of HIV in the body, which is a major barrier to finding a cure. The researchers aim to develop accurate biomarkers that can help detect latently infected cells in various tissues. By characterizing these cells in detail, the study seeks to improve strategies for targeting and eliminating the latent HIV reservoir. Patients may be involved in providing biological samples to help test these biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who have been on antiretroviral therapy and are interested in contributing to advancements in HIV treatment.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments that eliminate the hidden HIV reservoir, potentially paving the way for a cure.
How similar studies have performed: Previous research has shown some success in identifying biomarkers for HIV, but this approach aims to refine and improve upon those methods.
Where this research is happening
San Diego, United States
- VA San Diego Healthcare System — San Diego, United States (Active)
Researchers
- Principal investigator: Beliakova-Bethell, Nadejda S — VA San Diego Healthcare System
- Study coordinator: Beliakova-Bethell, Nadejda S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.