Understanding the factors that contribute to cancer risk
PROMINENT - UCSF
This study is looking at how different things, like our lifestyle and environment, can affect our chances of getting cancer, not just changes in our DNA, and it involves both people and mice to help understand these connections better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10625150 on NIH RePORTER |
What this research studies
This research investigates the various factors that influence the risk of developing cancer, focusing not only on DNA mutations but also on non-mutagenic factors such as lifestyle choices and environmental influences. By analyzing both human populations and mouse models, the study aims to uncover how these factors contribute to cancer development. The research employs advanced sequencing techniques to identify mechanisms that control mutated cells and how promoting factors can lead to cancer. Patients may be involved in providing data or samples that help elucidate these complex interactions.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with a family history of cancer or those who are concerned about their cancer risk due to lifestyle factors.
Not a fit: Patients with no personal or family history of cancer and no risk factors may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for cancer prevention and treatment by identifying key risk factors.
How similar studies have performed: Previous research has shown promising results in understanding cancer risk through similar approaches, indicating potential for significant advancements.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Balmain, Allan — University of California, San Francisco
- Study coordinator: Balmain, Allan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.