Understanding the factors that cause avian influenza to spread to humans
Quantifying the genetic and environmental factors driving avian influenza spillover
This study is looking at how genes and the environment help the H5N1 bird flu spread from birds to people, so we can better understand how to prevent future outbreaks that might affect our health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10688235 on NIH RePORTER |
What this research studies
This research investigates how genetic and environmental factors contribute to the spread of avian influenza, specifically the H5N1 virus, from birds to humans. By analyzing the interactions between wild birds and poultry, the study aims to identify the conditions that increase the risk of transmission. The researchers will employ advanced statistical and phylogenetic methods to assess husbandry practices and genetic mutations associated with the virus. This work is crucial for predicting and preventing future outbreaks that could affect human health.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals who work closely with poultry or live in areas with high avian influenza activity.
Not a fit: Patients who do not interact with birds or poultry are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing avian influenza outbreaks in humans.
How similar studies have performed: Previous research has shown success in understanding viral transmission dynamics in other contexts, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Moncla, Louise Hillier — University of Pennsylvania
- Study coordinator: Moncla, Louise Hillier
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.