Understanding the factors affecting the 'honeymoon period' in autoimmune diabetes
Multimodal analysis of the "honeymoon period" in autoimmune diabetes
This study is looking at the temporary improvement some people with type 1 diabetes feel after starting insulin therapy, called the "honeymoon period," and aims to find out what factors might help make this time last longer, so we can create better treatments in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11046556 on NIH RePORTER |
What this research studies
This research investigates the 'honeymoon period' experienced by some individuals with type 1 diabetes (T1D) after starting insulin therapy, where they may experience a temporary remission. The study aims to identify specific biomarkers related to immune, metabolic, and demographic factors that influence the duration of this remission. By analyzing these factors, researchers hope to develop composite biomarkers that can improve outcomes in future clinical trials for T1D. This could lead to better-targeted therapies and a deeper understanding of the disease's progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who are experiencing or have recently started insulin therapy.
Not a fit: Patients with type 2 diabetes or those who do not have autoimmune diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and potentially better management of type 1 diabetes for patients.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for diabetes progression, suggesting that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Davidson, Howard W — University of Colorado Denver
- Study coordinator: Davidson, Howard W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.