NIH-funded research R21 grant

Understanding the experiences of young women in HIV cure trials in South Africa

Official title: Integrating Trauma-Informed Research in Assessment of Young Women Engaged in HIV Cure Research (Post-Intervention Control) Trial with Analytical Treatment Interruption in Durban, South Africa

Funded at University of California, San Diego · NIH-10761531 · Data updated 2026-11-12

This study is looking at the experiences of young women in Durban, South Africa, who are taking part in a trial to find a cure for HIV, focusing on the challenges they face and how to make sure everyone has a fair chance to join these important research efforts.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 20, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$421,815
NIH project number1R21MH132406-01A1
Project IDNIH-10761531 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young women living with HIV who are engaged in or considering participation in HIV cure trials.

Less likely to help

Patients who are not young women or those not engaged in HIV cure research may not receive direct benefits from this research.

What this research studies

This research investigates the experiences of young women participating in an HIV cure trial in Durban, South Africa, focusing on the social, emotional, and ethical challenges they face. It aims to identify barriers to participation, particularly for marginalized groups, and to promote equitable enrollment in HIV cure research. The study employs a trauma-informed approach to ensure that the needs and experiences of these women are prioritized throughout the research process. By gathering qualitative data, the research seeks to inform better practices in HIV cure trials and improve outcomes for participants.

Why it matters

Potential benefit: If successful, this research could lead to more inclusive and effective HIV cure trials that better address the needs of young women, ultimately improving their health outcomes.

How similar studies have gone: While there is ongoing research in HIV treatment and prevention, this specific approach focusing on young women in a low-income setting is relatively novel.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Dube, Karine — University of California, San Diego
  • Study coordinator: Dube, Karine

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.